| Reaction Details |
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 | Report a problem with these data |
| Target | Adenylate cyclase type 5 |
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| Ligand | BDBM50119857 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_213257 |
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| IC50 | 79000±n/a nM |
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| Citation |  Levy, D; Bao, M; Tomlinson, J; Scarborough, R Hydroxamate based inhibitors of adenylyl cyclase. Part 2: the effect of cyclic linkers on P-site binding. Bioorg Med Chem Lett12:3089-92 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenylate cyclase type 5 |
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| Name: | Adenylate cyclase type 5 |
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| Synonyms: | ADCY5 | ADCY5_HUMAN | Adenylate cyclase | Adenylate cyclase type V |
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| Type: | PROTEIN |
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| Mol. Mass.: | 138919.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_31732 |
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| Residue: | 1261 |
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| Sequence: | MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPGGA
VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRQRR
GAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGAVEG
GEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQS
SLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDHMGL
ACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSAL
HLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLH
SQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTS
LASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEM
GMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGK
AGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKMN
RQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEFL
GRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQI
TIVPHSIFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLVGVF
TITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVAESAVNYSLGDEQGFCGSP
WPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNADL
LVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWKL
QATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANF
SEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTY
DKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWG
NTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPL
S
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| BDBM50119857 |
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| n/a |
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| Name | BDBM50119857 |
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| Synonyms: | CHEMBL108067 | [(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N5O3 |
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| Mol. Mass. | 277.2792 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1CC[C@@H](C1)OCC(O)=O |
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| Structure | 
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