| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 183 |
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| Ligand | BDBM50045543 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2063699 (CHEMBL4718952) |
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| EC50 | 2.1±n/a nM |
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| Citation |  Deng, X; Sun, S; Wu, J; Kuei, C; Joseph, V; Liu, C; Mani, NS Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability. Bioorg Med Chem Lett26:4888-4891 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 183 |
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| Name: | G-protein coupled receptor 183 |
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| Synonyms: | EBI2 | GP183_HUMAN | GPR183 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41245.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108311 |
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| Residue: | 361 |
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| Sequence: | MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNR
KKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVN
FMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERIT
CMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNK
KALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFN
CCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNG
K
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| BDBM50045543 |
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| n/a |
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| Name | BDBM50045543 |
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| Synonyms: | CHEMBL3311219 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H46O3 |
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| Mol. Mass. | 418.6523 |
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| SMILES | [H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@@H](O)C=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)(C)O |r,t:10| |
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| Structure | 
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