| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Urokinase plasminogen activator surface receptor |
|---|
| Ligand | BDBM50120749 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_213136 (CHEMBL817636) |
|---|
| IC50 | 700±n/a nM |
|---|
| Citation |  Schmiedeberg, N; Schmitt, M; Rölz, C; Truffault, V; Sukopp, M; Bürgle, M; Wilhelm, OG; Schmalix, W; Magdolen, V; Kessler, H Synthesis, solution structure, and biological evaluation of urokinase type plasminogen activator (uPA)-derived receptor binding domain mimetics. J Med Chem45:4984-94 (2002) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Urokinase plasminogen activator surface receptor |
|---|
| Name: | Urokinase plasminogen activator surface receptor |
|---|
| Synonyms: | CD_antigen=CD87 | MO3 | Monocyte activation antigen Mo3 | PLAUR | U-PAR | UPAR | UPAR_HUMAN | Urokinase plasminogen activator surface receptor | Urokinase receptor (uPAR) | Urokinase-type plasminogen activator/surface receptor |
|---|
| Type: | Receptor |
|---|
| Mol. Mass.: | 36979.14 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q03405 |
|---|
| Residue: | 335 |
|---|
| Sequence: | MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEL
ELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISC
GSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNG
FHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGP
MNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDV
QYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
|
|
|
|---|
| BDBM50120749 |
|---|
| n/a |
|---|
| Name | BDBM50120749 |
|---|
| Synonyms: | CHEMBL412223 | cyclic uPA-derived peptide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C54H84N18O21S2 |
|---|
| Mol. Mass. | 1385.483 |
|---|
| SMILES | CC(C)C[C@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](N)CSSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(C)C)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
