| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50265928 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2064598 (CHEMBL4719851) |
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| EC50 | >10000±n/a nM |
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| Citation |  Crowley, RS; Riley, AP; Sherwood, AM; Groer, CE; Shivaperumal, N; Biscaia, M; Paton, K; Schneider, S; Provasi, D; Kivell, BM; Filizola, M; Prisinzano, TE Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting ? Opioid Analgesic with Reduced Abuse Liability. J Med Chem59:11027-11038 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50265928 |
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| n/a |
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| Name | BDBM50265928 |
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| Synonyms: | CHEMBL4086641 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24O7 |
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| Mol. Mass. | 388.4111 |
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| SMILES | [H][C@@]12CC[C@@]3(C)[C@@H](CC(=O)C(O)=C3[C@@]1(C)C[C@H](OC2=O)c1ccoc1)C(=O)OC |r,c:11| |
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| Structure | 
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