Reaction Details |
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Target | Macrophage migration inhibitory factor |
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Ligand | BDBM50553882 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2067370 (CHEMBL4722623) |
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Ki | 2900±n/a nM |
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Citation | Xiao, Z; Fokkens, M; Chen, D; Kok, T; Proietti, G; van Merkerk, R; Poelarends, GJ; Dekker, FJ Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem186:0 (2020) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Macrophage migration inhibitory factor |
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Name: | Macrophage migration inhibitory factor |
Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
Type: | Enzyme |
Mol. Mass.: | 12478.18 |
Organism: | Homo sapiens (Human) |
Description: | P14174 |
Residue: | 115 |
Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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BDBM50553882 |
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n/a |
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Name | BDBM50553882 |
Synonyms: | CHEMBL4751935 |
Type | Small organic molecule |
Emp. Form. | C13H10N4O |
Mol. Mass. | 238.2447 |
SMILES | Oc1ccc(cc1)-n1cc(nn1)-c1ccccn1 |
Structure |
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