| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage migration inhibitory factor |
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| Ligand | BDBM50553885 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2067376 (CHEMBL4722629) |
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| Kd | 3630±n/a nM |
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| Citation |  Xiao, Z; Fokkens, M; Chen, D; Kok, T; Proietti, G; van Merkerk, R; Poelarends, GJ; Dekker, FJ Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem186:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage migration inhibitory factor |
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| Name: | Macrophage migration inhibitory factor |
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| Synonyms: | GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase |
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| Type: | Enzyme |
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| Mol. Mass.: | 12478.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14174 |
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| Residue: | 115 |
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| Sequence: | MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALC
SLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
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| BDBM50553885 |
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| n/a |
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| Name | BDBM50553885 |
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| Synonyms: | CHEMBL4745151 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14FN5O2 |
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| Mol. Mass. | 351.3345 |
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| SMILES | Oc1ccc(cc1F)-n1cc(CNC(=O)c2cc3ccccc3[nH]2)nn1 |
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| Structure | 
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