| Reaction Details |
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 | Report a problem with these data |
| Target | Amiloride-sensitive amine oxidase [copper-containing] |
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| Ligand | BDBM50121455 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_53891 |
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| Ki | 8000.0±n/a nM |
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| Citation |  Manna, F; Chimenti, F; Bolasco, A; Secci, D; Bizzarri, B; Befani, O; Turini, P; Mondovi, B; Alcaro, S; Tafi, A Inhibition of amine oxidases activity by 1-acetyl-3,5-diphenyl-4,5-dihydro-(1H)-pyrazole derivatives. Bioorg Med Chem Lett12:3629-33 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Amiloride-sensitive amine oxidase [copper-containing] |
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| Name: | Amiloride-sensitive amine oxidase [copper-containing] |
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| Synonyms: | ABP | ABP1 | AOC1 | AOC1_HUMAN | Amiloride-binding protein | DAO | DAO1 | Diamine oxidase | Diamine oxidase (DAO) | Histaminase | KAO | Kidney amine oxidase |
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| Type: | Protein |
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| Mol. Mass.: | 85387.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P19801 |
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| Residue: | 751 |
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| Sequence: | MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSS
TTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLP
GPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDR
CLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNG
KFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGP
RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYG
GHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFE
MPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMH
ATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENIT
NPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSM
ADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENI
ENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRD
NGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
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| BDBM50121455 |
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| n/a |
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| Name | BDBM50121455 |
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| Synonyms: | 1-[3-(2-Hydroxy-phenyl)-5-m-tolyl-4,5-dihydro-pyrazol-1-yl]-ethanone | CHEMBL120717 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18N2O2 |
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| Mol. Mass. | 294.3477 |
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| SMILES | CC(=O)N1N=C(CC1c1cccc(C)c1)c1ccccc1O |c:4| |
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| Structure | 
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