| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 9 |
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| Ligand | BDBM50559309 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2068656 (CHEMBL4723909) |
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| Kd | 67±n/a nM |
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| Citation |  Hügle, M; Regenass, P; Warstat, R; Hau, M; Schmidtkunz, K; Lucas, X; Wohlwend, D; Einsle, O; Jung, M; Breit, B; Günther, S 4-Acyl Pyrroles as Dual BET-BRD7/9 Bromodomain Inhibitors Address BETi Insensitive Human Cancer Cell Lines. J Med Chem63:15603-15620 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 9 |
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| Name: | Bromodomain-containing protein 9 |
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| Synonyms: | BRD9 | BRD9_HUMAN | Bromodomain-containing protein 9 | Rhabdomyosarcoma antigen MU-RMS-40.8 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66994.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_108000 |
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| Residue: | 597 |
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| Sequence: | MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHER
ERHKEKKKKKKKKSEKEKHLDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEP
PPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQ
AALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVISCMFEPEGNACSLTDSTAEEHVL
ALVEHAADEARDRINRFLPGGKMGYLKRNGDGSLLYSVVNTAEPDADEEETHPVDLSSLS
SKLLPGFTTLGFKDERRNKVTFLSSATTALSMQNNSVFGDLKSDEMELLYSAYGDETGVQ
CALSLQEFVKDAGSYSKKVVDDLLDQITGGDHSRTLFQLKQRRNVPMKPPDEAKVGDTLG
DSSSSVLEFMSMKSYPDVSVDISMLSSLGKVKKELDPDDSHLNLDETTKLLQDLHEAQAE
RGGSRPSSNLSSLSNASERDQHHLGSPSRLSVGEQPDVTHDPYEFLQSPEPAASAKT
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| BDBM50559309 |
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| n/a |
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| Name | BDBM50559309 |
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| Synonyms: | CHEMBL4762147 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3O6S |
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| Mol. Mass. | 461.531 |
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| SMILES | COc1ccc(cc1NC(=O)c1[nH]c(C)c2c1CCCCC2=O)S(=O)(=O)N1CCOCC1 |
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| Structure | 
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