| Reaction Details |
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 | Report a problem with these data |
| Target | Sialidase-3 |
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| Ligand | BDBM50559931 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2070711 (CHEMBL4726245) |
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| IC50 | 3900±n/a nM |
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| Citation |  La Rocca, P; Rota, P; Piccoli, M; Cirillo, F; Ghiroldi, A; Franco, V; Allevi, P; Anastasia, L 2?-3,4-Unsaturated sialic acid derivatives: Synthesis optimization, and biological evaluation as Newcastle disease virus hemagglutinin-neuraminidase inhibitors. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialidase-3 |
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| Name: | Sialidase-3 |
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| Synonyms: | NEU3 | NEUR3_HUMAN | Sialidase 3 | Sialidase-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48257.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_461856 |
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| Residue: | 428 |
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| Sequence: | MEEVTTCSFNSPLFRQEDDRGITYRIPALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRR
GLRIGQLVQWGPLKPLMEATLPGHRTMNPCPVWEQKSGCVFLFFICVRGHVTERQQIVSG
RNAARLCFIYSQDAGCSWSEVRDLTEEVIGSELKHWATFAVGPGHGIQLQSGRLVIPAYT
YYIPSWFFCFQLPCKTRPHSLMIYSDDLGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVL
YCSARTPNRCRAEALSTDHGEGFQRLALSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSS
KDAPTIQQSSPGSSLRLEEEAGTPSESWLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRP
WILHCGPCGYSDLAALEEEGLFGCLFECGTKQECEQIAFRLFTHREILSHLQGDCTSPGR
NPSQFKSN
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| BDBM50559931 |
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| n/a |
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| Name | BDBM50559931 |
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| Synonyms: | CHEMBL4745230 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14F3NO8 |
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| Mol. Mass. | 345.226 |
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| SMILES | [H][C@]1(OC(=C[C@H](O)[C@H]1NC(=O)C(F)(F)F)C(O)=O)[C@H](O)[C@H](O)CO |r,c:3| |
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| Structure | 
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