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TargetPatatin-like phospholipase domain-containing protein 2
LigandBDBM50560132
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2071471 (CHEMBL4727005)
IC50 5000±n/a nM
Citation Mayer, NSchweiger, MFuchs, EMigglautsch, AKDoler, CGrabner, GFRomauch, MMelcher, MCZechner, RZimmermann, RBreinbauer, R Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL). Bioorg Med Chem28:0 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Patatin-like phospholipase domain-containing protein 2
Name:Patatin-like phospholipase domain-containing protein 2
Synonyms:Adipose triglyceride lipase | Atgl | Desnutrin | PLPL2_MOUSE | Patatin-like phospholipase domain-containing protein 2 | Pnpla2
Type:PROTEIN
Mol. Mass.:53655.79
Organism:Mus musculus
Description:ChEMBL_109612
Residue:486
Sequence:
MFPRETKWNISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGA
CLGEAGANIIEVSKEARKRFLGPLHPSFNLVKTIRGCLLKTLPADCHERANGRLGISLTR
VSDGENVIISHFSSKDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKN
TITVSPFSGESDICPQDSSTNIHELRVTNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQ
GYRDGLRFLRRNGLLNQPNPLLALPPVVPQEEDAEEAAVVEERAGEEDQLQPYRKDRILE
HLPARLNEALLEACVEPKDLMTTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLPD
VPEDIRWMKEQTGSICQYLVMRAKRKLGDHLPSRLSEQVELRRAQSLPSVPLSCATYSEA
LPNWVRNNLSLGDALAKWEECQRQLLLGLFCTNVAFPPDALRMRAPASPTAADPATPQDP
PGLPPC
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  Blast E-value cutoff:
BDBM50560132
n/a
NameBDBM50560132
Synonyms:CHEMBL4779344
TypeSmall organic molecule
Emp. Form.C16H18N2O2
Mol. Mass.270.3263
SMILESCOC(=O)Nc1cccc(c1)-c1ccc(cc1)N(C)C
Structure
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