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TargetAmine oxidase [flavin-containing] A
LigandBDBM50122758
Substrate/Competitorn/a
Meas. Tech.ChEMBL_123595 (CHEMBL734177)
IC50 30000±n/a nM
Citation Cosford, ND; Tehrani, L; Roppe, J; Schweiger, E; Smith, ND; Anderson, J; Bristow, L; Brodkin, J; Jiang, X; McDonald, I; Rao, S; Washburn, M; Varney, MA 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. J Med Chem46:204-6 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase [flavin-containing] A
Name:Amine oxidase [flavin-containing] A
Synonyms:AOFA_MOUSE | Amine oxidase [flavin-containing] A | MAO-A | Maoa | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A
Type:PROTEIN
Mol. Mass.:59608.24
Organism:Mus musculus
Description:ChEMBL_122776
Residue:526
Sequence:
MTDLEKPSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHV
KWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLA
YLDYNNLWRTMDDMGKEIPVDAPWQARHAEEWDKITMKDLIDKICWTKTAREFAYLFVNI
NVTSEPHEVSALWFLWYVRQCGGTSRIFSVTNGGQERKFVGGSGQISEQIMVLLGDKVKL
SSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPM
GAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSMPAIMGFILARKAER
LAKLHKDIRKRKICELYAKVLGSQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYG
RVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVQEPESKD
VPALEITHTFLERNLPSVPGLLKITGFSTSVALLCFVLYKFKQPQS
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  Blast E-value cutoff:
BDBM50122758
n/a
NameBDBM50122758
Synonyms:2-methyl-4-(pyridin-3-ylethynyl)thiazole | 3-(2-(2-methylthiazol-4-yl)ethynyl)pyridine | 3-(2-Methyl-thiazol-4-ylethynyl)-pyridine | 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine | 3-[(2-methyl-4-thiazolyl)ethynyl]pyridine | CHEMBL292065 | MTEP
TypeSmall organic molecule
Emp. Form.C11H8N2S
Mol. Mass.200.26
SMILESCc1nc(cs1)C#Cc1cccnc1
Structure
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