| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform gamma-2 |
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| Ligand | BDBM50560703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2072751 (CHEMBL4728285) |
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| Kd | 100±n/a nM |
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| Citation |  Schröder, M; Bullock, AN; Fedorov, O; Bracher, F; Chaikuad, A; Knapp, S DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity. J Med Chem63:10224-10234 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform gamma-2 |
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| Name: | Casein kinase I isoform gamma-2 |
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| Synonyms: | CK1G2 | CSNK1G2 | Casein kinase I | Casein kinase I gamma 2 | KC1G2_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47475.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774313 |
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| Residue: | 415 |
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| Sequence: | MDFDKKGGKGETEEGRRMSKAGGGRSSHGIRSSGTSSGVLMVGPNFRVGKKIGCGNFGEL
RLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSATEGVPQVYYFGPCGKYNAMVLE
LLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGTKR
QHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGH
MFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFF
EKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIGTVHTDLPSQPQLRDKTQPHSK
NQALNSTNGELNADDPTAGHSNAPITAPAEVEVADETKCCCFFKRRKRKSLQRHK
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| BDBM50560703 |
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| n/a |
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| Name | BDBM50560703 |
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| Synonyms: | CHEMBL1349996 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15NO2S |
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| Mol. Mass. | 249.329 |
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| SMILES | CCN1\C(Sc2ccc(OC)cc12)=C/C(C)=O |
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| Structure | 
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