| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor |
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| Ligand | BDBM50123208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_67178 |
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| IC50 | 2.2±n/a nM |
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| Citation |  Blizzard, TA; Morgan, JD; Mosley, RT; Birzin, ET; Frisch, K; Rohrer, SP; Hammond, ML 2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs). Bioorg Med Chem Lett13:479-83 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen receptor |
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| Name: | Estrogen receptor |
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| Synonyms: | ESR1_RAT | Esr | Esr1 | Estr | Nr3a1 | estrogen alpha |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 67045.89 |
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| Organism: | RAT |
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| Description: | estrogen alpha 0 RAT::P06211 |
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| Residue: | 600 |
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| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKMPMERALGEVYVDNSKPAVFNYPEGAAY
EFNAAAAAAAAGASAPVYGQSSITYGPGSEAAAFGANSLGAFPQLNSVSPSPLMLLHPPP
HVSPFLHPHGHQVPYYLENEPSAYAVRDTGPPAFYRSNSDNRRQNGRERLSSSSEKGNMI
MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK
SCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDLEGRNEMGTSGDMRAANLWPSP
LVIKHTKKNSPALSLTADQMVSALLDAEPPLIYSEYDPSRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFGDLNLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQG
KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI
HRVLDKINDTLIHLMAKAGLTLQQQHRRLAQLLLILSHIRHMSNKGMEHLYNMKCKNVVP
LYDLLLEMLDAHRLHAPASRMGVPPEEPSQSQLTTTSSTSAHSLQTYYIPPEAEGFPNTI
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| BDBM50123208 |
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| n/a |
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| Name | BDBM50123208 |
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| Synonyms: | 2-(4-hydroxyphenyl)-3-methyl-1,2'-spirobi[1H-indene]-5-ol | CHEMBL145576 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H20O2 |
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| Mol. Mass. | 340.4144 |
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| SMILES | CC1=C(c2ccc(O)cc2)C2(Cc3ccccc3C2)c2ccc(O)cc12 |c:1| |
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| Structure | 
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