| Reaction Details |
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 | Report a problem with these data |
| Target | Estrogen receptor beta |
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| Ligand | BDBM50123207 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_67342 |
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| IC50 | 15±n/a nM |
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| Citation |  Blizzard, TA; Morgan, JD; Mosley, RT; Birzin, ET; Frisch, K; Rohrer, SP; Hammond, ML 2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs). Bioorg Med Chem Lett13:479-83 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Estrogen receptor beta |
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| Name: | Estrogen receptor beta |
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| Synonyms: | ESR2_RAT | Erbeta | Esr2 | Estrogen receptor | Estrogen receptor beta | Nr3a2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59173.80 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_803011 |
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| Residue: | 530 |
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| Sequence: | MEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRHEYSAMTFYSPAVMNYSVPG
STSNLDGGPVRLSTSPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVN
RETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSSSEQVH
CLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTK
LADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLASANQEA
ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK
CKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNKESSQNLQSQ
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|
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| BDBM50123207 |
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| n/a |
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| Name | BDBM50123207 |
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| Synonyms: | 2-(3-hydroxyphenyl)-1,2'-spirobi[1H-indene]-6-ol | CHEMBL144431 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H18O2 |
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| Mol. Mass. | 326.3878 |
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| SMILES | Oc1ccc2C=C(c3cccc(O)c3)C3(Cc4ccccc4C3)c2c1 |t:5| |
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| Structure | 
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