| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor beta |
|---|
| Ligand | BDBM50123212 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_67342 |
|---|
| IC50 | 1070±n/a nM |
|---|
| Citation |  Blizzard, TA; Morgan, JD; Mosley, RT; Birzin, ET; Frisch, K; Rohrer, SP; Hammond, ML 2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs). Bioorg Med Chem Lett13:479-83 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor beta |
|---|
| Name: | Estrogen receptor beta |
|---|
| Synonyms: | ESR2_RAT | Erbeta | Esr2 | Estrogen receptor | Estrogen receptor beta | Nr3a2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 59173.80 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_803011 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRHEYSAMTFYSPAVMNYSVPG
STSNLDGGPVRLSTSPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVN
RETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSSSEQVH
CLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTK
LADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLASANQEA
ESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLLSHVRHISNKGMEHLLSMK
CKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNKESSQNLQSQ
|
|
|
|---|
| BDBM50123212 |
|---|
| n/a |
|---|
| Name | BDBM50123212 |
|---|
| Synonyms: | 2-phenyl-1,2'-spirobi[1H-indene]-5'-ol | CHEMBL439806 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H18O |
|---|
| Mol. Mass. | 310.3884 |
|---|
| SMILES | Oc1ccc2CC3(Cc2c1)C(=Cc1ccccc31)c1ccccc1 |c:12| |
|---|
| Structure | 
|
|---|
Search and Browse
