| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
|---|
| Ligand | BDBM50008099 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2074194 (CHEMBL4729728) |
|---|
| Ki | 51±n/a nM |
|---|
| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arginase-2, mitochondrial |
|---|
| Name: | Arginase-2, mitochondrial |
|---|
| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38576.93 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_978892 |
|---|
| Residue: | 354 |
|---|
| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
|
|
|
|---|
| BDBM50008099 |
|---|
| n/a |
|---|
| Name | BDBM50008099 |
|---|
| Synonyms: | CHEMBL1234777 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H12N4O3 |
|---|
| Mol. Mass. | 176.1738 |
|---|
| SMILES | N[C@@H](CCNC(=N)NO)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
