| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-1 |
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| Ligand | BDBM50561045 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2074196 (CHEMBL4729730) |
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| Ki | <10.0±n/a nM |
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| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-1 |
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| Name: | Arginase-1 |
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| Synonyms: | ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34737.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978893 |
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| Residue: | 322 |
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| Sequence: | MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
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| BDBM50561045 |
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| n/a |
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| Name | BDBM50561045 |
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| Synonyms: | CHEMBL4758805 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H32BClN2O5 |
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| Mol. Mass. | 426.742 |
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| SMILES | NC(CCCCB(O)O)(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)C(O)=O |
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| Structure | 
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