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TargetArginase-1
LigandBDBM50561051
Substrate/Competitorn/a
Meas. Tech.ChEMBL_2074198 (CHEMBL4729732)
IC50 1.000000±n/a nM
Citation Borek, BGajda, TGolebiowski, ABlaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase-1
Name:Arginase-1
Synonyms:ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase
Type:PROTEIN
Mol. Mass.:34737.53
Organism:Homo sapiens (Human)
Description:ChEMBL_978893
Residue:322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50561051
n/a
NameBDBM50561051
Synonyms:CHEMBL4749434
TypeSmall organic molecule
Emp. Form.C12H24BN3O5
Mol. Mass.301.147
SMILESC[C@H](N)C(=O)N1C[C@@H](CCB(O)O)C[C@@](N)([C@@H]1C)C(O)=O |r|
Structure
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