| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
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| Ligand | BDBM50561047 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2074199 (CHEMBL4729733) |
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| IC50 | 0.100000±n/a nM |
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| Citation |  Borek, B; Gajda, T; Golebiowski, A; Blaszczyk, R Boronic acid-based arginase inhibitors in cancer immunotherapy. Bioorg Med Chem28:0 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-2, mitochondrial |
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| Name: | Arginase-2, mitochondrial |
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| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38576.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978892 |
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| Residue: | 354 |
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| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
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| BDBM50561047 |
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| n/a |
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| Name | BDBM50561047 |
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| Synonyms: | CHEMBL4764455 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H23BN4O6S |
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| Mol. Mass. | 338.189 |
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| SMILES | NCCNS(=O)(=O)N1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O |r| |
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| Structure | 
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