| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 1 |
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| Ligand | BDBM50561903 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2076219 (CHEMBL4731753) |
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| Ki | 61±n/a nM |
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| Citation |  Mancuso, F; De Luca, L; Angeli, A; Berrino, E; Del Prete, S; Capasso, C; Supuran, CT; Gitto, R In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in ACS Med Chem Lett11:2294-2299 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 1 |
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| Name: | Carbonic anhydrase 1 |
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| Synonyms: | CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA |
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| Type: | Enzyme |
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| Mol. Mass.: | 28873.37 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00915 |
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| Residue: | 261 |
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| Sequence: | MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEI
INVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH
VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF
DPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAV
PMQHNNRPTQPLKGRTVRASF
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| BDBM50561903 |
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| n/a |
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| Name | BDBM50561903 |
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| Synonyms: | CHEMBL4761063 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H16N2O3S |
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| Mol. Mass. | 304.364 |
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| SMILES | Cc1cccc(c1)C(=O)NCc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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