| Reaction Details |
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 | Report a problem with these data |
| Target | Histone acetyltransferase KAT2A |
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| Ligand | BDBM50346554 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2077544 (CHEMBL4733335) |
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| IC50 | 8390±n/a nM |
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| Citation |  He, ZX; Wei, BF; Zhang, X; Gong, YP; Ma, LY; Zhao, W Current development of CBP/p300 inhibitors in the last decade. Eur J Med Chem209:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone acetyltransferase KAT2A |
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| Name: | Histone acetyltransferase KAT2A |
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| Synonyms: | GCN5 | GCN5 | GCN5L2 | General control of amino acid synthesis protein 5-like 2 | HGCN5 | Histone acetyltransferase GCN5 | Histone acetyltransferase KAT2A | Histone acetyltransferase KAT2A/KAT2B | HsGCN5 | KAT2A | KAT2A_HUMAN | Lysine acetyltransferase 2A | STAF97 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 93956.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_100876 |
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| Residue: | 837 |
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| Sequence: | MAEPSQAPTPAPAAQPRPLQSPAPAPTPTPAPSPASAPIPTPTPAPAPAPAAAPAGSTGT
GGPGVGSGGAGSGGDPARPGLSQQQRASQRKAQVRGLPRAKKLEKLGVFSACKANETCKC
NGWKNPKPPTAPRMDLQQPAANLSELCRSCEHPLADHVSHLENVSEDEINRLLGMVVDVE
NLFMSVHKEEDTDTKQVYFYLFKLLRKCILQMTRPVVEGSLGSPPFEKPNIEQGVLNFVQ
YKFSHLAPRERQTMFELSKMFLLCLNYWKLETPAQFRQRSQAEDVATYKVNYTRWLCYCH
VPQSCDSLPRYETTHVFGRSLLRSIFTVTRRQLLEKFRVEKDKLVPEKRTLILTHFPKFL
SMLEEEIYGANSPIWESGFTMPPSEGTQLVPRPASVSAAVVPSTPIFSPSMGGGSNSSLS
LDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPAAMLGPETSLL
SANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQLPRMPKEYIA
RLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGYGTHLMNHLKE
YHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATLMECELNPRIP
YTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPGIRETGWKPLG
KEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIRFPIDLKTMTE
RLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLKEGGLIDK
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| BDBM50346554 |
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| n/a |
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| Name | BDBM50346554 |
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| Synonyms: | CHEMBL106011 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H7FN2OS |
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| Mol. Mass. | 246.26 |
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| SMILES | Fc1ccc(cc1)-n1sc2ncccc2c1=O |
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| Structure | 
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