| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 4 |
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| Ligand | BDBM50563421 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2082434 (CHEMBL4738225) |
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| IC50 | 2512±n/a nM |
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| Citation |  Schüß, C; Vu, O; Schubert, M; Du, Y; Mishra, NM; Tough, IR; Stichel, J; Weaver, CD; Emmitte, KA; Cox, HM; Meiler, J; Beck-Sickinger, AG Highly Selective Y J Med Chem64:2801-2814 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 4 |
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| Name: | Neuropeptide Y receptor type 4 |
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| Synonyms: | NPY-Y4 | NPY4-R | NPY4R | NPY4R_HUMAN | PP1 | PPYR1 | Pancreatic polypeptide receptor 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42207.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y4 PPYR1 HUMAN::P50391 |
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| Residue: | 375 |
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| Sequence: | MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNL
CLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFI
QCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSIL
ENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRR
LQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHG
NLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTE
VSKGSLRLSGRSNPI
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| BDBM50563421 |
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| n/a |
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| Name | BDBM50563421 |
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| Synonyms: | CHEMBL4745232 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O5S2 |
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| Mol. Mass. | 397.469 |
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| SMILES | CS(=O)(=O)N1CCCC[C@H]1C(=O)Nc1nc2cc3OCCOc3cc2s1 |r| |
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| Structure | 
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