| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK1 |
|---|
| Ligand | BDBM50560704 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2083224 (CHEMBL4739015) |
|---|
| IC50 | 8.0±n/a nM |
|---|
| Citation |  N?mec, V; Maier, L; Berger, BT; Chaikuad, A; Drápela, S; Sou?ek, K; Knapp, S; Paruch, K Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core. Eur J Med Chem215:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dual specificity protein kinase CLK1 |
|---|
| Name: | Dual specificity protein kinase CLK1 |
|---|
| Synonyms: | CDC-like kinase 1 | CDC-like kinase 1 (CLK1) | CDC2-like kinase 1 (CLK1) | CLK | CLK1 | CLK1_HUMAN | Dual specificity protein kinase CLK1 | Dual specificity protein kinase CLK1/CLK4 | Dual specificty protein kinase CLK1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 57322.21 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49759 |
|---|
| Residue: | 484 |
|---|
| Sequence: | MRHSKRTYCPDWDDKDWDYGKWRSSSSHKRRKRSHSSAQENKRCKYNHSKMCDSHYLESR
SINEKDYHSRRYIDEYRNDYTQGCEPGHRQRDHESRYQNHSSKSSGRSGRSSYKSKHRIH
HSTSHRRSHGKSHRRKRTRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECID
HKAGGRHVAVKIVKNVDRYCEAARSEIQVLEHLNTTDPNSTFRCVQMLEWFEHHGHICIV
FELLGLSTYDFIKENGFLPFRLDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVQSD
YTEAYNPKIKRDERTLINPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPC
DVWSIGCILIEYYLGFTVFPTHDSKEHLAMMERILGPLPKHMIQKTRKRKYFHHDRLDWD
EHSSAGRYVSRRCKPLKEFMLSQDVEHERLFDLIQKMLEYDPAKRITLREALKHPFFDLL
KKSI
|
|
|
|---|
| BDBM50560704 |
|---|
| n/a |
|---|
| Name | BDBM50560704 |
|---|
| Synonyms: | CHEMBL4754195 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H16N4O |
|---|
| Mol. Mass. | 352.3886 |
|---|
| SMILES | Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3ccncc3)c2n1 |
|---|
| Structure | 
|
|---|
Search and Browse
