| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase type 1B |
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| Ligand | BDBM50563780 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2084282 (CHEMBL4765545) |
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| IC50 | 3000±n/a nM |
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| Citation |  Beesu, M; Caruso, G; Salyer, AC; Shukla, NM; Khetani, KK; Smith, LJ; Fox, LM; Tanji, H; Ohto, U; Shimizu, T; David, SA Identification of a Human Toll-Like Receptor (TLR) 8-Specific Agonist and a Functional Pan-TLR Inhibitor in 2-Aminoimidazoles. J Med Chem59:3311-30 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase type 1B |
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| Name: | Calcium/calmodulin-dependent protein kinase type 1B |
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| Synonyms: | CaM kinase I beta | CaM kinase IB | CaM-KI beta | CaMKI-beta | Calcium/calmodulin-dependent protein kinase type 1B | KCC1B_HUMAN | PNCK | Pregnancy up-regulated non-ubiquitously-expressed CaM kinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38501.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_109914 |
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| Residue: | 343 |
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| Sequence: | MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVEN
EIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQV
LGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVA
PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS
ESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRA
FNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW
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| BDBM50563780 |
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| n/a |
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| Name | BDBM50563780 |
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| Synonyms: | CHEMBL4795714 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26ClN3O |
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| Mol. Mass. | 371.904 |
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| SMILES | Cl.CCCCCn1cc(nc1N)-c1ccccc1OCc1ccccc1 |
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| Structure | 
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