| Reaction Details |
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 | Report a problem with these data |
| Target | Peroxisome proliferator-activated receptor delta |
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| Ligand | BDBM50127921 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_154546 (CHEMBL760265) |
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| IC50 | >50000±n/a nM |
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| Citation |  Koyama, H; Boueres, JK; Han, W; Metzger, EJ; Bergman, JP; Gratale, DF; Miller, DJ; Tolman, RL; MacNaul, KL; Berger, JP; Doebber, TW; Leung, K; Moller, DE; Heck, JV; Sahoo, SP 5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists. Bioorg Med Chem Lett13:1801-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Peroxisome proliferator-activated receptor delta |
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| Name: | Peroxisome proliferator-activated receptor delta |
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| Synonyms: | NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta |
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| Type: | Enzyme |
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| Mol. Mass.: | 49910.45 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q03181 |
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| Residue: | 441 |
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| Sequence: | MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM
GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK
NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK
HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE
ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK
DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD
RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI
KKTETETSLHPLLQEIYKDMY
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| BDBM50127921 |
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| n/a |
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| Name | BDBM50127921 |
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| Synonyms: | 5-(4-{3-[4-(4-Methoxy-phenoxy)-2-propyl-phenoxy]-propoxy}-phenyl)-thiazolidine-2,4-dione | CHEMBL50885 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H29NO6S |
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| Mol. Mass. | 507.598 |
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| SMILES | CCCc1cc(Oc2ccc(OC)cc2)ccc1OCCCOc1ccc(cc1)-c1sc(=O)[nH]c1O |
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| Structure | 
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