| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50129427 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_62393 |
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| Ki | 891±n/a nM |
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| Citation |  Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. Bioorg Med Chem Lett13:2179-83 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50129427 |
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| n/a |
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| Name | BDBM50129427 |
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| Synonyms: | 9H-Fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-ynyl}-amide | CHEMBL71416 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H25Cl2N3O |
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| Mol. Mass. | 490.424 |
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| SMILES | Clc1cccc(N2CCN(CC#CCNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl |
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| Structure | 
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