| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50129425 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_223734 |
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| Ki | 2.6±n/a nM |
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| Citation |  Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR N-(4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl, butenyl and butynyl)arylcarboxamides as novel dopamine D(3) receptor antagonists. Bioorg Med Chem Lett13:2179-83 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
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| Type: | Protein |
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| Mol. Mass.: | 49540.58 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P19020 |
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| Residue: | 446 |
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| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
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| BDBM50129425 |
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| n/a |
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| Name | BDBM50129425 |
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| Synonyms: | 5-Fluoro-1H-indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide | CHEMBL68740 | N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-5-fluoro-1H-indole-2-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25Cl2FN4O |
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| Mol. Mass. | 463.375 |
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| SMILES | Fc1ccc2[nH]c(cc2c1)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl |
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| Structure | 
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