| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide FF receptor 2 |
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| Ligand | BDBM50037567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2090955 (CHEMBL4772218) |
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| Ki | 2.0±n/a nM |
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| Citation |  Nguyen, T; Marusich, J; Li, JX; Zhang, Y Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem63:12387-12402 (2020) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide FF receptor 2 |
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| Name: | Neuropeptide FF receptor 2 |
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| Synonyms: | G-protein coupled receptor 74 | Gpr74 | NPFF2_RAT | Neuropeptide G-protein coupled receptor | Npff2 | Npffr2 | Npgpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47725.66 |
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| Organism: | RAT |
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| Description: | NPFF2 0 RAT::Q9EQD2 |
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| Residue: | 417 |
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| Sequence: | MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCM
VGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKI
SGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAI
MLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYA
RIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYAD
LSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAY
GLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
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| BDBM50037567 |
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| n/a |
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| Name | BDBM50037567 |
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| Synonyms: | 2-[(Pyrrolidine-2-carbonyl)-amino]-pentanedioic acid 5-amide 1-{[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide} | CHEMBL414263 |
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| Type | Small organic molecule |
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| Emp. Form. | C55H78N14O11 |
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| Mol. Mass. | 1111.295 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
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| Structure | 
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