| Reaction Details |
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 | Report a problem with these data |
| Target | Bone morphogenetic protein 1 |
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| Ligand | BDBM50130112 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_158896 |
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| Ki | 63±n/a nM |
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| Citation |  Robinson, LA; Wilson, DM; Delaet, NG; Bradley, EK; Dankwardt, SM; Campbell, JA; Martin, RL; Van Wart, HE; Walker, KA; Sullivan, RW Novel inhibitors of procollagen C-proteinase. Part 2: glutamic acid hydroxamates. Bioorg Med Chem Lett13:2381-4 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Bone morphogenetic protein 1 |
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| Name: | Bone morphogenetic protein 1 |
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| Synonyms: | BMP-1 | BMP1 | BMP1_HUMAN | Mammalian tolloid protein | PCOLC | PCP | Procollagen C-proteinase | mTld |
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| Type: | PROTEIN |
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| Mol. Mass.: | 111254.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_518962 |
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| Residue: | 986 |
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| Sequence: | MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN
TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST
PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR
FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY
GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS
DDTITKKGFHLRYTSTKFQDTLHSRK
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| BDBM50130112 |
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| n/a |
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| Name | BDBM50130112 |
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| Synonyms: | (R)-5-(4-Acetyl-piperazin-1-yl)-2-[benzo[1,3]dioxol-5-ylmethyl-(4-methoxy-2,3,6-trimethyl-benzenesulfonyl)-amino]-5-oxo-pentanoic acid hydroxyamide | CHEMBL449092 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H38N4O9S |
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| Mol. Mass. | 618.698 |
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| SMILES | COc1cc(C)c(c(C)c1C)S(=O)(=O)N(Cc1ccc2OCOc2c1)[C@H](CCC(=O)N1CCN(CC1)C(C)=O)C(=O)NO |
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| Structure | 
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