Reaction Details |
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Target | High affinity immunoglobulin epsilon receptor subunit alpha |
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Ligand | BDBM50130415 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_68795 (CHEMBL683434) |
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IC50 | 25000±n/a nM |
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Citation | Buku, A; Mendlowitz, M; Condie, BA; Price, JA Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions. J Med Chem46:3008-12 (2003) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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High affinity immunoglobulin epsilon receptor subunit alpha |
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Name: | High affinity immunoglobulin epsilon receptor subunit alpha |
Synonyms: | FCE1A | FCER1A | FCERA_HUMAN | Fc-epsilon RI-alpha | FcERI | High affinity immunoglobulin epsilon receptor subunit alpha | IgE Fc receptor subunit alpha | IgE Fc receptor, alpha-subunit |
Type: | PROTEIN |
Mol. Mass.: | 29595.99 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_68795 |
Residue: | 257 |
Sequence: | MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVS
STKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAE
VVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKV
WQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTR
KGFRLLNPHPKPNPKNN
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BDBM50130415 |
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n/a |
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Name | BDBM50130415 |
Synonyms: | CHEMBL412391 | IKCNCKRHVIKAHICRKICGKN-NH2 |
Type | Small organic molecule |
Emp. Form. | C108H194N42O24S4 |
Mol. Mass. | 2593.223 |
SMILES | CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(N)=O |
Structure |
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