Ki Summary

Reaction Details

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Target

High affinity immunoglobulin epsilon receptor subunit alpha

Ligand

BDBM50130418

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_68795 (CHEMBL683434)

IC50

82000±n/a nM

Citation

Buku, A; Mendlowitz, M; Condie, BA; Price, JA Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions. J Med Chem46:3008-12 (2003) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

High affinity immunoglobulin epsilon receptor subunit alpha

Name:

High affinity immunoglobulin epsilon receptor subunit alpha

Synonyms:

Type:

PROTEIN

Mol. Mass.:

29595.99

Organism:

Homo sapiens (Human)

Description:

ChEMBL_68795

Residue:

257

Sequence:

MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVS
STKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAE
VVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKV
WQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTR
KGFRLLNPHPKPNPKNN

BDBM50130418

n/a

Name

BDBM50130418

Synonyms:

CHEMBL267118 | IACNCKRHVIKPHICRKICGKN-NH2

Type

Small organic molecule

Emp. Form.

C107H189N39O24S4

Mol. Mass.

2534.152

SMILES

CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(N)=O

Structure