| Reaction Details |
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 | Report a problem with these data |
| Target | Vitamin D3 receptor |
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| Ligand | BDBM50565949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2094255 (CHEMBL4775518) |
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| IC50 | 67±n/a nM |
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| Citation |  Sasaki, H; Masuno, H; Kawasaki, H; Yoshihara, A; Numoto, N; Ito, N; Ishida, H; Yamamoto, K; Hirata, N; Kanda, Y; Kawachi, E; Kagechika, H; Tanatani, A Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists. J Med Chem64:516-526 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vitamin D3 receptor |
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| Name: | Vitamin D3 receptor |
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| Synonyms: | NR1I1 | VDR | VDR_BOVIN | Vitamin D receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48313.44 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_514897 |
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| Residue: | 426 |
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| Sequence: | MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
PFNGDCRITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
RPKLSEEQQRIITTLLEAHHKTYDDTYSDFSQFRPPVRNSEDEGNRPLRSILTPSFSGNS
SSSCSDHCTSSPDTMEPTSFSNQDLNEEDSDDPSVTLDLSQLSMLPHLADLVSYSIQKVI
GFAKMIPGFRDLTPEDQIVLLKSSAIEVIMLRSNQSFTLDDDMSWTCGSPDYKYQVSDVT
RAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALVEAIQDRLSN
TLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPESSMKLTPLLFEV
FGNEIS
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| BDBM50565949 |
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| n/a |
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| Name | BDBM50565949 |
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| Synonyms: | CHEMBL4794075 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H48O3 |
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| Mol. Mass. | 432.6789 |
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| SMILES | [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC(C)(C)O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O |r| |
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| Structure | 
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