| Reaction Details |
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 | Report a problem with these data |
| Target | Sialyltransferase ST3Gal-I |
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| Ligand | BDBM50565994 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2094327 (CHEMBL4775590) |
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| IC50 | 13200±n/a nM |
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| Citation |  Fu, CW; Tsai, HE; Chen, WS; Chang, TT; Chen, CL; Hsiao, PW; Li, WS Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis. J Med Chem64:527-542 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sialyltransferase ST3Gal-I |
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| Name: | Sialyltransferase ST3Gal-I |
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| Synonyms: | 2.4.99.4 | Sialyltransferase ST3Gal-I | St3gal1 | Synonyms=siat4A |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39366.95 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_120282 |
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| Residue: | 340 |
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| Sequence: | MVNMRKRTLKYLTFFLLFIFLTSFVLNYSNSGVPSAWFPKQMVLEFSENFRKFIKSQPCT
CRHCISQGKVSYWFDQRFNKTMQPLLTVHNALMEEDTYRWWLRLQRERKPNNLSDTVKEL
FRLVPGNVDPMLNKRLVGCRRCAVVGNSGNLKDSSYGPEIDSHDFVLRMNRAPTVGFEAD
VGSRTTHHLVYPESFRELGENVNMVLVPFKITDLQWVISATTTGTITHTYVPVPPKIKVK
QEKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSIHICDEVDLYGFGADSKGNWHHY
WENNPSAGAFRKTGVHDGDFEYNVTTTLAAINKIRIFKGR
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| BDBM50565994 |
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| n/a |
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| Name | BDBM50565994 |
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| Synonyms: | CHEMBL3596261 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H48N4O9 |
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| Mol. Mass. | 668.777 |
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| SMILES | [H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)[C@H](CCC(O)=O)Nc1ccc([N+]([O-])=O)c2nonc12)[C@H](C)CCC(O)=O |r| |
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| Structure | 
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