| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
|---|
| Ligand | BDBM50568282 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2105006 (CHEMBL4813509) |
|---|
| Ki | 1.5±n/a nM |
|---|
| Citation |  Takao, K; Takemura, Y; Nagai, J; Kamauchi, H; Hoshi, K; Mabashi, R; Uesawa, Y; Sugita, Y Synthesis and biological evaluation of 3-styrylchromone derivatives as selective monoamine oxidase B inhibitors. Bioorg Med Chem42:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Amine oxidase [flavin-containing] B |
|---|
| Name: | Amine oxidase [flavin-containing] B |
|---|
| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 58768.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27338 |
|---|
| Residue: | 520 |
|---|
| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
|
|
|
|---|
| BDBM50568282 |
|---|
| n/a |
|---|
| Name | BDBM50568282 |
|---|
| Synonyms: | CHEMBL4847545 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H13ClO3 |
|---|
| Mol. Mass. | 312.747 |
|---|
| SMILES | COc1ccc2c(c1)occ(\C=C\c1ccc(Cl)cc1)c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
