| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50026553 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_62879 (CHEMBL878289) |
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| Ki | 3±n/a nM |
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| Citation |  Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikström, HV Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity. J Med Chem46:4136-40 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50026553 |
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| n/a |
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| Name | BDBM50026553 |
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| Synonyms: | (+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | (+/-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | (-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol | 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol (DP-5,6-ADTN) | CHEMBL11845 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H25NO2 |
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| Mol. Mass. | 263.3752 |
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| SMILES | CCCN(CCC)C1CCc2c(C1)ccc(O)c2O |
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| Structure | 
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