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TargetProtein kinase C delta
LigandBDBM50133246
Substrate/Competitorn/a
Meas. Tech.ChEMBL_160776
Ki 17±n/a nM
Citation Sridhar JWei ZLNowak ILewin NEAyres JAPearce LVBlumberg PMKozikowski AP New bivalent PKC ligands linked by a carbon spacer: enhancement in binding affinity. J Med Chem 46:4196-204 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protein kinase C delta
Name:Protein kinase C delta
Synonyms:Protein kinase C delta type | nPKC-delta
Type:PROTEIN
Mol. Mass.:77554.99
Organism:Mus musculus
Description:ChEMBL_1351519
Residue:674
Sequence:
MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKTLVQKKPTMYPEWKTTFD
AHIYEGRVIQIVLMRAAEDPVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQY
FLEDGDCKQSMRSEEEAKFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMS
PTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSR
KLDTTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGSTRCTLENFTFQKVLGKGSFGK
VLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWESPFLTHLICTFQTKDH
LFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLD
RDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEML
IGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLGVTGNIRIHPF
FKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHG
FSFVNPKFEQFLDI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50133246
n/a
NameBDBM50133246
Synonyms:CHEMBL335486 | Hexanedioic acid [(S)-5-hydroxymethyl-2-((S)-isopropyl)-1-methyl-3-oxo-1,2,3,4,5,6-hexahydro-benzo[e][1,4]diazocin-9-yl]-amide ((2S,5S)-5-hydroxymethyl-2-isopropyl-1-methyl-3-oxo-1,2,3,4,5,6-hexahydro-benzo[e][1,4]diazocin-8-yl)-amide
TypeSmall organic molecule
Emp. Form.C36H52N6O6
Mol. Mass.664.8347
SMILESCC(C)[C@@H]1N(C)c2ccc(NC(=O)CCCCC(=O)Nc3ccc4C[C@@H](CO)NC(=O)[C@H](C(C)C)N(C)c4c3)cc2C[C@@H](CO)NC1=O
Structure
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