| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin alpha-1A chain |
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| Ligand | BDBM50134461 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_211866 |
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| IC50 | >50000±n/a nM |
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| Citation |  Lawrence, NJ; Rennison, D; McGown, AT; Hadfield, JA The total synthesis of an aurone isolated from Uvaria hamiltonii: aurones and flavones as anticancer agents. Bioorg Med Chem Lett13:3759-63 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Tubulin alpha-1A chain |
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| Name: | Tubulin alpha-1A chain |
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| Synonyms: | TBA1A_PIG | TUBA1A | Tubulin | Tubulin alpha chain | Tubulin alpha-1A chain |
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| Type: | Protein |
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| Mol. Mass.: | 50049.25 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P02550 |
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| Residue: | 451 |
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| Sequence: | MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFSVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRAHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYEPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
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| BDBM50134461 |
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| n/a |
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| Name | BDBM50134461 |
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| Synonyms: | 2-(3-Hydroxy-4-methoxy-phenyl)-5,6,7-trimethoxy-chromen-4-one | CHEMBL124885 | eupatorin-5-methylether |
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| Type | Small organic molecule |
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| Emp. Form. | C19H18O7 |
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| Mol. Mass. | 358.342 |
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| SMILES | COc1ccc(cc1O)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1 |
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| Structure | 
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