| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsin-C |
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| Ligand | BDBM50135495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_49615 |
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| IC50 | >1000±n/a nM |
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| Citation |  Masaki, H; Mizuno, Y; Tatui, A; Murakami, A; Koide, Y; Satoh, S; Takahashi, A Structure-activity relationship of benzo[b]thiophene-2-sulfonamide derivatives as novel human chymase inhibitors. Bioorg Med Chem Lett13:4085-8 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsin-C |
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| Name: | Chymotrypsin-C |
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| Synonyms: | CLCR | CTRC | CTRC_HUMAN | Caldecrin | Chymotrypsin | Chymotrypsin C | Chymotrypsin-C |
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| Type: | Enzyme |
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| Mol. Mass.: | 29487.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99895 |
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| Residue: | 268 |
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| Sequence: | MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
RGCNTRKKPVVYTRVSAYIDWINEKMQL
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| BDBM50135495 |
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| n/a |
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| Name | BDBM50135495 |
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| Synonyms: | 4-(5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester | CHEMBL129879 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16ClNO6S3 |
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| Mol. Mass. | 473.971 |
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| SMILES | COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)c(c1)S(C)(=O)=O |
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| Structure | 
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