| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5'-nucleotidase |
|---|
| Ligand | BDBM50523526 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2114161 (CHEMBL4823011) |
|---|
| IC50 | >1000±n/a nM |
|---|
| Citation |  Oliva, P; Scortichini, M; Dobelmann, C; Jain, S; Gopinatth, V; Toti, KS; Phung, NB; Junker, A; Jacobson, KA Structure-activity relationships of pyrimidine nucleotides containing a 5'-?,?-methylene diphosphonate at the P2Y Bioorg Med Chem Lett45:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5'-nucleotidase |
|---|
| Name: | 5'-nucleotidase |
|---|
| Synonyms: | 5'-nucleotidase | 5NTD_RAT | Ecto-5'-nucleotidase (e5'NT) | Ecto-5-nucleotidase (e5'NT) | NT | Nt5 | Nt5e | Nte |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 63971.44 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P21588 |
|---|
| Residue: | 576 |
|---|
| Sequence: | MRPAAATAPKWLLLALSALLPLWPTAKSWELTIMHTNDVHSRLEQTSDDSTKCLNASLCV
GGVARLFTKVQQIRKEEPNVLLLDAGDQYQGTIWFTVYKGLEVAHFMNLLGYDAMALGNH
EFDNGVEGLIDPLLRNVKFPILSANIKARGPLAPQISGLYLPYKVLSVGGEVVGIVGYTS
KETPFLSNPGTNLVFEDEVTALQPEVDKLKTLNVNKIIALGHSGFEMDKLIAQKVRGVDV
VVGGHTNTFLYTGNPPSKEVPAGKYPFIVTSDDGRKVPVVQAYAFGKYLGYLKVEFDDKG
NVVTSYGNPILLNSTIREDAAIKADINQWRIKLDNYSTQELGRTIVYLNGSAQECRFREC
NMGNLICDAMINNNLRHPDEMFWNHVSMCIVNGGGIRSPIDERNNGTITWENLAAVLPFG
GTFDLVQLKGSTLKKAFEHSVHRYGQSTGEFLQVGGIHVVYDISRKPWDRVVQLKVLCTK
CRVPIYEPLEMDKVYKVVLPSYLVNGGDGFQMIKDELLKHDSGDQDISVVSEYISKMKVI
YPAVEGRIKFSAASHYQGSFPLIILSFWAVILVLYQ
|
|
|
|---|
| BDBM50523526 |
|---|
| n/a |
|---|
| Name | BDBM50523526 |
|---|
| Synonyms: | CHEMBL3606064 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H15FN2O11P2 |
|---|
| Mol. Mass. | 420.1788 |
|---|
| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)CP(O)(O)=O)n1cc(F)c(=O)[nH]c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
