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TargetMelatonin receptor
LigandBDBM50136402
Substrate/Competitorn/a
Meas. Tech.ChEBML_105266
Ki 0.310000±n/a nM
Citation Sun LQChen JMattson RJEpperson JRDeskus JALi WSTakaki KHodges DBIben LMahle CDOrtiz AMolstad DRyan EYeleswaram KXu CLuo G Heterocyclic aminopyrrolidine derivatives as melatoninergic agents. Bioorg Med Chem Lett 13:4381-4 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50136402
n/a
NameBDBM50136402
Synonyms:CHEMBL136531 | N-[(S)-1-(2,3-Dihydro-benzofuran-4-yl)-pyrrolidin-3-yl]-butyramide
TypeSmall organic molecule
Emp. Form.C16H22N2O2
Mol. Mass.274.3581
SMILESCCCC(=O)N[C@H]1CCN(C1)c1cccc2OCCc12
Structure
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