Reaction Details |
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Target | 5-hydroxytryptamine receptor 2A |
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Ligand | BDBM50132097 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_2640 (CHEMBL618695) |
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Ki | 2200±n/a nM |
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Citation | Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA Binding of beta-carbolines at 5-HT(2) serotonin receptors. Bioorg Med Chem Lett13:4421-5 (2003) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 2A |
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Name: | 5-hydroxytryptamine receptor 2A |
Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 52852.05 |
Organism: | Rattus norvegicus (rat) |
Description: | Rat cortex membranes 5-HT2A receptors. |
Residue: | 471 |
Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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BDBM50132097 |
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n/a |
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Name | BDBM50132097 |
Synonyms: | 7-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline | CHEMBL6310 |
Type | Small organic molecule |
Emp. Form. | C12H14N2O |
Mol. Mass. | 202.2524 |
SMILES | COc1ccc2c3CCNCc3[nH]c2c1 |
Structure |
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