| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-galactosidase A |
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| Ligand | BDBM50137350 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_34241 |
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| Ki | 400000±n/a nM |
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| Citation |  Kröger, L; Henkensmeier, D; Schäfer, A; Thiem, J Novel O-glycosyl amino acid mimetics as building blocks for O-glycopeptides act as inhibitors of galactosidases. Bioorg Med Chem Lett14:73-5 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-galactosidase A |
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| Name: | Alpha-galactosidase A |
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| Synonyms: | AGAL_HUMAN | Alpha-D-galactosidase A | Alpha-D-galactoside galactohydrolase | Alpha-galactosidase A | Alpha-glucosidase A (α-Gal A) | GLA | INN=Agalsidase | Melibiase |
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| Type: | Protein |
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| Mol. Mass.: | 48760.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 429 |
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| Sequence: | MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEP
DSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQL
ANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENL
ADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIK
SILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDL
RHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIG
GPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENT
MQMSLKDLL
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| BDBM50137350 |
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| n/a |
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| Name | BDBM50137350 |
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| Synonyms: | 2-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-propionic acid | CHEMBL3215441 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H17NO8 |
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| Mol. Mass. | 267.2332 |
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| SMILES | N[C@@H](COC[C@H]1O[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O)C(O)=O |
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| Structure | 
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