| Reaction Details |
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 | Report a problem with these data |
| Target | Rhomboid protease GlpG |
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| Ligand | BDBM50572955 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2118695 (CHEMBL4827761) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Parsons, WH; Rutland, NT; Crainic, JA; Cardozo, JM; Chow, AS; Andrews, CL; Sheehan, BK Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL. Bioorg Med Chem Lett49:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Rhomboid protease GlpG |
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| Name: | Rhomboid protease GlpG |
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| Synonyms: | GLPG_ECOLI | Rhomboid protease (EcGlpG) | glpG |
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| Type: | Protein |
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| Mol. Mass.: | 31313.89 |
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| Organism: | Escherichia coli (Enterobacteria) |
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| Description: | P09391 |
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| Residue: | 276 |
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| Sequence: | MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPA
DPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVM
LWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLI
SALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAG
WFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
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| BDBM50572955 |
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| n/a |
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| Name | BDBM50572955 |
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| Synonyms: | CHEMBL4861272 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H9NO4S |
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| Mol. Mass. | 239.248 |
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| SMILES | O=C1CCC(=O)N1S(=O)(=O)c1ccccc1 |
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| Structure | 
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