| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50139011 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145838 (CHEMBL755496) |
|---|
| Ki | 94.3±n/a nM |
|---|
| Citation |  Tömböly, C; Kövér, KE; Péter, A; Tourwé, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Rónai, AZ; Tóth, G Structure-activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues. J Med Chem47:735-43 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 42692.90 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P34975 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
|
|
|
|---|
| BDBM50139011 |
|---|
| n/a |
|---|
| Name | BDBM50139011 |
|---|
| Synonyms: | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1R,2S)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide | CHEMBL349738 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H39N5O5 |
|---|
| Mol. Mass. | 585.6933 |
|---|
| SMILES | C[C@H]([C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
