| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50139012 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_148385 (CHEMBL757380) |
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| IC50 | 235±n/a nM |
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| Citation |  Tömböly, C; Kövér, KE; Péter, A; Tourwé, D; Biyashev, D; Benyhe, S; Borsodi, A; Al-Khrasani, M; Rónai, AZ; Tóth, G Structure-activity study on the Phe side chain arrangement of endomorphins using conformationally constrained analogues. J Med Chem47:735-43 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50139012 |
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| n/a |
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| Name | BDBM50139012 |
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| Synonyms: | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((1S,2R)-1-carbamoyl-2-phenyl-propylcarbamoyl)-2-phenyl-ethyl]-amide | CHEMBL163334 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H39N5O5 |
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| Mol. Mass. | 585.6933 |
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| SMILES | C[C@@H]([C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O)c1ccccc1 |
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| Structure | 
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