| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50130293 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2119480 (CHEMBL4828546) |
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| Ki | 2.3±n/a nM |
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| Citation |  Shaik, AB; Boateng, CA; Battiti, FO; Bonifazi, A; Cao, J; Chen, L; Chitsazi, R; Ravi, S; Lee, KH; Shi, L; Newman, AH Structure Activity Relationships for a Series of Eticlopride-Based Dopamine D J Med Chem64:15313-15333 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50130293 |
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| n/a |
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| Name | BDBM50130293 |
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| Synonyms: | 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one | ARIPIPRAZOLE | CHEMBL1112 | US10174011, aripiprazole | US10752588, Compound Aripiprazole | US11498896, Compound Aripiprazole | US9018213, aripprazole | US9156822, Aripiprazole |
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| Type | Small organic molecule |
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| Emp. Form. | C23H27Cl2N3O2 |
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| Mol. Mass. | 448.385 |
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| SMILES | Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl |
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| Structure | 
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