| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50139356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_60209 |
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| Ki | 130±n/a nM |
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| Citation |  Thomson, CG; Beer, MS; Curtis, NR; Diggle, HJ; Handford, E; Kulagowski, JJ Thiazoles and thiopyridines: novel series of high affinity h5HT(7) ligands. Bioorg Med Chem Lett14:677-80 (2004) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50139356 |
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| n/a |
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| Name | BDBM50139356 |
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| Synonyms: | CHEMBL350166 | Dimethyl-[2-(4-pyridin-4-yl-thiazol-2-ylsulfanyl)-ethyl]-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N3S2 |
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| Mol. Mass. | 265.398 |
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| SMILES | CN(C)CCSc1nc(cs1)-c1ccncc1 |
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| Structure | 
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