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TargetMelatonin receptor
LigandBDBM50140301
Substrate/Competitorn/a
Meas. Tech.ChEBML_105264
Ki 0.240000±n/a nM
Citation Sun LQChen JTakaki KJohnson GIben LMahle CDRyan EXu C Design and synthesis of benzoxazole derivatives as novel melatoninergic ligands. Bioorg Med Chem Lett 14:1197-200 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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  Blast E-value cutoff:
BDBM50140301
n/a
NameBDBM50140301
Synonyms:CHEMBL19026 | N-{(1R,2R)-2-[2-(4-Phenyl-butyl)-2,3-dihydro-benzooxazol-7-yl]-cyclopropylmethyl}-butyramide
TypeSmall organic molecule
Emp. Form.C25H32N2O2
Mol. Mass.392.5338
SMILESCCCC(=O)NC[C@@H]1C[C@H]1c1cccc2NC(CCCCc3ccccc3)Oc12
Structure
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