| Reaction Details |
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 | Report a problem with these data |
| Target | Ceramide glucosyltransferase |
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| Ligand | BDBM50141446 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_71695 |
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| IC50 | 90±n/a nM |
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| Citation |  Slavish, JP; Friel, DK; Oland, LA; Polt, R New PDMP analogues inhibit process outgrowth in an insect cell line. Bioorg Med Chem Lett14:1487-90 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ceramide glucosyltransferase |
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| Name: | Ceramide glucosyltransferase |
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| Synonyms: | CEGT_HUMAN | GCS | GLCT-1 | Glucosylceramide synthase | UDP-glucose ceramide glucosyltransferase | UDP-glucose:N-acylsphingosine D-glucosyltransferase | UGCG |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44859.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1435474 |
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| Residue: | 394 |
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| Sequence: | MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLK
GVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVG
INPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGF
AATLEQVYFGTSHPRYYISANVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMA
KAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMT
IYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV
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| BDBM50141446 |
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| n/a |
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| Name | BDBM50141446 |
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| Synonyms: | CHEMBL34778 | Hexadecanoic acid [2-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-hydroxy-1-pyrrolidin-1-ylmethyl-ethyl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C31H52N2O4 |
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| Mol. Mass. | 516.7556 |
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| SMILES | CCCCCCCCCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc2OCCOc2c1 |
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| Structure | 
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