| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50142139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212711 |
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| IC50 | >11000±n/a nM |
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| Citation |  Zhang, P; Bao, L; Zuckett, JF; Jia, ZJ; Woolfrey, J; Arfsten, A; Edwards, S; Sinha, U; Hutchaleelaha, A; Lambing, JL; Hollenbach, SJ; Scarborough, RM; Zhu, BY Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity. Bioorg Med Chem Lett14:989-93 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50142139 |
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| n/a |
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| Name | BDBM50142139 |
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| Synonyms: | 5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(N-methyl-guanidino)-methyl]-benzoylamino}-benzamide | CHEMBL174558 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20Cl2N6O2 |
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| Mol. Mass. | 471.339 |
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| SMILES | CN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(N)=N |
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| Structure | 
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