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TargetTrypsin-1
LigandBDBM50142139
Substrate/Competitorn/a
Meas. Tech.ChEBML_212711
IC50>11000±n/a nM
Citation Zhang PBao LZuckett JFJia ZJWoolfrey JArfsten AEdwards SSinha UHutchaleelaha ALambing JLHollenbach SJScarborough RMZhu BY Design, synthesis, and SAR of anthranilamide-based factor Xa inhibitors with improved functional activity. Bioorg Med Chem Lett 14:989-93 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Trypsin-1
Name:Trypsin-1
Synonyms:Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | Trypsin | Trypsin I
Type:Enzyme
Mol. Mass.:26557.80
Organism:Homo sapiens (Human)
Description:P07477
Residue:247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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  Blast E-value cutoff:
BDBM50142139
n/a
NameBDBM50142139
Synonyms:5-Chloro-N-(5-chloro-pyridin-2-yl)-2-{4-[(N-methyl-guanidino)-methyl]-benzoylamino}-benzamide | CHEMBL174558
TypeSmall organic molecule
Emp. Form.C22H20Cl2N6O2
Mol. Mass.471.339
SMILESCN(Cc1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)C(N)=N
Structure
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